The Pittsburgh Pirates played in the First World Series in Major League Baseball, between the Boston Americans of the American League and the Pittsburgh Pirates of the National League.
The world's first banana split is served in Latrobe, PA.
The Nickelodeon, the world's first theater devoted to motion pictures, opened on Smithfield Street in Pittsburgh.
Forbes Field, the country's first baseball stadium, opened in Pittsburgh on June 30, 1909, to a standing-room only crowd of 30,338. The Chicago Cubs won the game against the Pittsburgh Pirates, by a score of 3-2.
The nation's first gas station opened in Pittsburgh. It was built by Gulf Refining Company.
Dr. James Bert Garner invented the gas mask (a WWI design) at the Mellon Institute.
Daylight Savings Time came to Pittsburgh. This was the nation's first daylight savings time.
In the 1920s Bingo was born in Pittsburgh. It was originally called Beano and dried beans were used as the markers.
Pittsburgh's KDKA was the first commercial radio station in the United States. It also became the first commercially licensed radio station to broadcast presidential election returns on November 2, 1920. The election was between Ohio's Governor James M. Cox and Senator Warren G. Harding of Ohio.
KDKA Radio in Pittsburgh becomes first radio station to broadcast a church service on January 2, 1921. Calvary Episcopal Church was the site of the first remote broadcast.
Construction began in Pittsburgh on the world's first university skyscraper, The Cathedral of Learning, at the University of Pittsburgh's campus in Oakland. It is 42-stories high and styled in the Late Gothic Revival style.
A Pittsburgh molasses company, P. Duff & Sons, patented the first cake mix. A blend of dehydrated molasses, flour, sugar, eggs, other ingredients, required only water and baking to produce gingerbread.
First Polio Vaccine trial. Dr. Jonas Salk, a researcher/professor at the University of Pittsburgh, developed the polio vaccine.
Pittsburgh's Alcoa Building. The first all-aluminum skyscraper was built, 30 stories high, with aluminum walls only 1/8-inch thick.
Public Television. The first community-sponsored educational television station in the USA (WQED). WQED is known for producing Mister Rogers' Neighborhood and Where in the World is Carmen Sandiego?
The world's first full-scale atomic-powered plant for production of electricity was opened a few miles away from Pittsburgh in Shippingport, PA.
Pittsburgh's Civic Arena, with its world-famous retractable stainless steel dome, first opened to the public. It was built as the home of the Pittsburgh Civic Light Opera (CLO) but the Ice Capades were the first event at the arena on September 19, 1961.
World's first pull tabs on cans. Pittsburgh's Alcoa developed pull tabs for cans which were called zip tops. These pull tabs were first used by Pittsburgh's Iron City Brewery.
The First Big Mac was created in Uniontown, PA, by Jim Delligatti, a McDonald's franchise owner, and it was test marketed in 3 Pittsburgh area McDonald's Restaurants. It didn't take long for the Big Mac to become a hit at McDonald's everywhere.
Dr. Richard Moriarty of the Children's Hospital Poison Center created the Mr. Yuk sticker to replace the skull and crossbones previously used.
First World Series Night Game. Before the 4th game of the 1971 World Series between the Pittsburgh Pirates and the Baltimore Orioles, the games were always a daytime event. The Pirates won the series.
Carnegie Mellon University, in cooperation with CMU Professors Raj Reddy and Angel Jordan and Westinghouse Electric's President Tom Murrin, started the first Robotics Institute in Pittsburgh with the goal of making it the best place to do robotics research in the world.
Presbyterian-University Hospital was the site of the world's first simultaneous heart, liver and kidney transplant, which was performed on a 26-year-old woman.